Jornada 1 | Atlético de Madrid | 0-1 | Real Madrid | 05/09/2021 | Jornada 2 | Unión Adarve | 0-1 | Atlético de Madrid | 12/09/2021 | UYL | J1 | Atlético de Madrid | 1-2 | Porto | 15/09/2021 | Jornada 3 | Atlético de Madrid | 1-0 | Leganés | 19/09/2021 | Jornada 4 | Trival Valderas | 2-4 | Atlético de Madrid | 26/09/2021 | UYL | J2 | Milan | 1-1 | Atlético de Madrid | 28/09/2021 | Jornada 5 | Atlético de Madrid | 1-0 | Fuenlabrada | 03/10/2021 | Jornada 6 | Valladolid | 0-2 | Atlético de Madrid | 10/10/2021 | Jornada 7 | Atlético de Madrid | 3-0 | Gimnástica Segoviana | 17/10/2021 | UYL | J3 | Atlético de Madrid | 2-0 | Liverpool | 19/10/2021 | Jornada 8 | CD Badajoz 1905 | 0-3 | Atlético de Madrid | 24/10/2021 | Jornada 9 | Atlético de Madrid | 1-0 | Rayo Vallecano | 31/10/2021 | UYL | J4 | Liverpool | 2-0 | Atlético de Madrid | 03/11/2021 | Jornada 10 | Getafe | 1-3 | Atlético de Madrid | 07/11/2021 | Jornada 11 | Las Rozas | 0-1 | Atlético de Madrid | 14/11/2021 | Jornada 12 | Atlético de Madrid | 1-0 | Rayo Majadahonda | 21/11/2021 | UYL | J5 | Atlético de Madrid | 3-0 | Milan | 24/11/2021 | Jornada 13 | Alcorcón | 0-1 | Atlético de Madrid | 28/11/2021 | Jornada 14 | Atlético de Madrid | 0-1 | Cultural Leonesa | 05/12/2021 | UYL | J6 | Porto | 1-2 | Atlético de Madrid | 07/12/2021 | Jornada 15 | Burgos | 0-1 | Atlético de Madrid | 12/12/2021 | Jornada 16 | Atlético de Madrid | 5-0 | La Cruz Villanovense | 19/12/2021 | Jornada 17 | Flecha Negra | 0-5 | Atlético de Madrid | 09/01/2022 | Copa | 1/16 de final | Atlético de Madrid | 4-1 | Cultural Leonesa | 15/01/2022 | Jornada 18 | Real Madrid | 0-1 | Atlético de Madrid | 23/01/2022 | Jornada 19 | Atlético de Madrid | 2-0 | Unión Adarve | 06/02/2022 | UYL | Playoff | Hajduk Split | 0 (2) - 0 (3) | Atlético de Madrid | 09/02/2022 | Jornada 20 | Leganés | 1-1 | Atlético de Madrid | 13/02/2022 | Jornada 21 | Atlético de Madrid | 2-0 | Trival Valderas | 20/02/2022 | Copa | 1/8 de final | UD Las Palmas | 2-6 | Atlético de Madrid | 26/02/2022 | Jornada 22 | Fuenlabrada | 1-1 | Atlético de Madrid | 09/03/2022 | UYL | 1/8 de final | Real Madrid | 2-3 | Atlético de Madrid | 02/03/2022 | Jornada 23 | Atlético de Madrid | 6-0 | Valladolid | 06/03/2022 | Jornada 24 | Gimnástica Segoviana | 2-4 | Atlético de Madrid | 04/05/2022 | UYL | 1/4 de final | Borussia Dortmund | 0-1 | Atlético de Madrid | 16/03/2022 | Jornada 25 | Atlético de Madrid | 4-0 | CD Badajoz 1905 | 20/03/2022 | Copa | 1/4 de final | Atlético de Madrid | 1-2 | Real Betis | 26/03/2022 | Jornada 26 | Rayo Vallecano | 0-3 | Atlético de Madrid | 06/04/2022 | Jornada 27 | Atlético de Madrid | 2-1 | Getafe | 03/04/2022 | Jornada 28 | Atlético de Madrid | 3-1 | Las Rozas | 10/04/2022 | Jornada 29 | Rayo Majadahonda | 1-4 | Atlético de Madrid | 17/04/2022 | UYL | 1/2 de final | Atlético de Madrid | 0-5 | Salzburgo | 22/04/2022 | Jornada 30 | Atlético de Madrid | 1-0 | Alcorcón | 18/05/2022 | Jornada 31 | Cultural Leonesa | 0-2 | Atlético de Madrid | 01/05/2022 | Jornada 32 | Atlético de Madrid | 6-1 | Burgos | 08/05/2022 | Jornada 33 | La Cruz Villanovense | 2-2 | Atlético de Madrid | 15/05/2022 | Jornada 34 | Atlético de Madrid | 7-0 | Flecha Negra | 22/05/2022 | C. Campeones | 1/4 | Atlético de Madrid | 1(2)-1(3) | Celta de Vigo | 29/05/2022 |
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